Topical Anesthetic for PMU, Microblading & Tattoo Procedures

Topical anesthetic products are used in permanent makeup, microblading, tattooing, and other cosmetic procedures to reduce skin sensitivity at the treatment site. This collection covers primary anesthetic creams applied before the procedure begins, secondary anesthetic gels applied during the procedure to open skin, hemostatic agents used to manage minor bleeding, and specialty formats such as single-use anesthetic napkins.

Products are intended for use by licensed PMU artists, tattoo technicians, and cosmetic procedure professionals. Formulas vary by active ingredient concentration, application stage, and format. Always review the product's ingredient list, concentration, and application instructions before use, and comply with applicable regulations in your state or jurisdiction.

Types of Topical Anesthetic and Related Products

The collection is organized around the stage of the procedure at which each product is applied. Primary and secondary anesthetics serve different functions and are not interchangeable in professional use.

• Primary anesthetic creams — applied to intact skin before the procedure begins, typically under occlusion, to reduce surface sensitivity prior to needle contact. Products in this category include Amor Fati White Caine 12.5% (50 g and 100 g) and Pink Caine (50 g and 100 g), Klever Safe Touch 12.5%, PRO-CAINE 12.5% (50 g and 500 g), A-CAINE 10.95% (50 g and 500 g), B-CAINE (50 g and 500 g), GeLido Anestetico 10% (30 ml and 250 ml), Dr. Numb 10% (30 g), F&E Tattooist 10% (35 ml) and Red 7% (35 ml), IBC Cream (50 g), Super Numb Original (30 ml), PM Cream (50 g), Klever Ice Cream (30 ml), TKTX creams in 40% (red, blue, gold — 10 g each) and 75% Blue (10 g), Depain cream with Lidocaine 4% / Prilocaine 2.5% / Benzocaine 1% (35 g and 100 g), and a dedicated Eye Anesthetic Cream (10 g) for periocular procedures.
• Secondary anesthetic gels — applied to the skin after the first pass, when the skin barrier has been broken, to extend the numbing effect during the procedure. Gel formulas are absorbed more readily through open skin. Products include Amor Fati Blue Caine (15 ml and 30 ml) and Lila Caine (15 ml and 30 ml), Klever Ice Fresh gel (20 ml, 30 ml, and 50 ml), Depain Ice Gel (20 g, 30 ml, and 50 g), Mark Ecopharm Tattoo Ice gel (2 ml sachet and 10 ml), Viva Ink Numb Topical Gel (15 g), Vesper Tattoo NO:PAIN (15 ml and 30 ml), Frost Line Gel (30 ml), and TKTX Anesthetic Gel 40% (15 ml).
• Hemostatic agents — used during procedures to reduce minor surface bleeding and improve visibility of the work area. Mark Ecopharm Hemostatic Agent is available in 10 ml and 100 ml. Tashnik Hemostatic Agent is available in 50 ml.
• Specialty formats — England-KIAY Anesthetic Napkin for Lips is a single-use pre-saturated format for lip procedures. Feel Better Now Secondary Anesthesia (30 g) and B-CAINE (50 g and 500 g) round out the broader anesthetic range.

The distinction between primary and secondary anesthetics is important for professional use. Primary creams are formulated for intact skin and require adequate contact time before the procedure. Secondary gels are formulated for application to open skin during the procedure. Using a secondary gel on intact skin, or a primary cream during an active procedure, may not produce the intended result — follow each product's application instructions.

How to Choose a Topical Anesthetic for PMU

Selecting the right anesthetic depends on the procedure type, the application stage, the treatment area, and the format that suits your working method.

• Application stage — determine whether you need a primary product (pre-procedure, intact skin) or a secondary product (during procedure, open skin). Some professionals stock both for use at different stages of the same session.
• Concentration — products in this collection range from 7% to 75% active ingredient concentration. Higher concentrations are not necessarily appropriate for all procedures or skin types. Review the product's formulation and intended use before selecting based on concentration alone.
• Format — creams are standard for primary application; gels are typical for secondary use. Single-use sachets (Mark Ecopharm Tattoo Ice, 2 ml) and napkins (England-KIAY) are practical for mobile or high-hygiene settings.
• Treatment area — the Eye Anesthetic Cream (10 g) is specifically positioned for periocular use. For lip procedures, the England-KIAY anesthetic napkin offers a dedicated format. Confirm that the product selected is appropriate for the specific treatment area.
• Size and volume — large professional sizes (500 g for PRO-CAINE, A-CAINE, B-CAINE; 100 ml for Mark Ecopharm Hemostatic) are suited to high-volume practices. Smaller sizes are practical for lower-volume use or for trialing a new product.
• Hemostatic need — if managing minor surface bleeding is part of your workflow, hemostatic agents should be stocked separately from anesthetic products, as they serve a different function.

When introducing a new anesthetic product into your workflow, perform a patch test per the manufacturer's instructions and review the active ingredient list for any client contraindications before the procedure.

Professional Brands in This Collection

Several professional PMU and tattoo supply brands are represented, each with a distinct product focus and format range.

Amor Fati offers a structured primary and secondary anesthetic line under distinct product names: White Caine and Pink Caine for primary use, Blue Caine and Lila Caine for secondary use. Products are available in 50 g, 100 g, 15 ml, and 30 ml formats, giving professionals flexibility across procedure types.

TKTX carries anesthetic creams in 40% concentration (red, blue, and gold variants) and a 75% Blue formula, as well as a 40% gel. The brand is widely used in tattoo and PMU settings and offers small 10–15 g/ml sizes suited to per-session use.

Depain provides both cream and gel formats. The Depain cream specifies its active ingredients (Lidocaine 4%, Prilocaine 2.5%, Benzocaine 1%), which is useful for professionals who need to review the formulation for client consultations. The Depain Ice Gel is available in three sizes for secondary use.

Klever offers the Safe Touch 12.5% primary cream, the Ice Cream (30 ml), and the Ice Fresh gel line in three sizes (20 ml, 30 ml, 50 ml), covering both application stages within a single brand.

Additional brands include Mark Ecopharm (anesthetic gel sachets and hemostatic agents), Vesper Tattoo (NO:PAIN secondary anesthetic), Viva Ink Numb (topical gel), Tashnik (hemostatic agent), Dr. Numb, GeLido, and others.

Topical Anesthetic for PMU at Beauty Hunter

Beauty Hunter carries a professional selection of topical anesthetic creams, secondary anesthetic gels, hemostatic agents, and specialty formats for PMU, microblading, and tattoo procedures. The assortment covers both application stages — pre-procedure and during-procedure — across a range of concentrations, formats, and sizes suited to different professional workflows.

Products are sourced from brands used in professional PMU studios and tattoo practices. Large professional sizes are available across selected products for high-volume use, and smaller sizes allow professionals to trial formulas before committing to bulk quantities. Beauty Hunter's professional focus means the anesthetic range reflects the products working PMU artists and technicians actually use in their practice.